Llwytho...
The crystal structures of chloramphenicol phosphotransferase reveal a novel inactivation mechanism
Chloramphenicol (Cm), produced by the soil bacterium Streptomyces venezuelae, is an inhibitor of bacterial ribosomal peptidyltransferase activity. The Cm-producing streptomycete modifies the primary (C-3) hydroxyl of the antibiotic by a novel Cm-inactivating enzyme, chloramphenicol 3-O-phosphotransf...
Wedi'i Gadw mewn:
| Prif Awduron: | , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Oxford University Press
2000
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC212772/ https://ncbi.nlm.nih.gov/pubmed/10835366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.11.2690 |
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