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Rationally designed insulator-like elements can block enhancer action in vitro
Insulators are DNA sequences that are likely to be involved in formation of chromatin domains, functional units of gene expression in eukaryotes. Insulators can form domain boundaries and block inappropriate action of regulatory elements (such as transcriptional enhancers) in eukaryotic nuclei. Usin...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2003
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC212734/ https://ncbi.nlm.nih.gov/pubmed/12970185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg468 |
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