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Theoretical analysis of the role of chromatin interactions in long-range action of enhancers and insulators

Long-distance regulatory interactions between enhancers and their target genes are commonplace in higher eukaryotes. Interposed boundaries or insulators are able to block these long-distance regulatory interactions. The mechanistic basis for insulator activity and how it relates to enhancer action-a...

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Bibliografiske detaljer
Main Authors: Mukhopadhyay, Swagatam, Schedl, Paul, Studitsky, Vasily M., Sengupta, Anirvan M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250180/
https://ncbi.nlm.nih.gov/pubmed/22123989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103845108
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