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Locus dependence in epigenetic chromatin silencing

Current biological models of epigenetic switches built on chromatin modifications lead to strong constraints on the repertoire of dynamic behaviors for the system. We use the structure of the bifurcation diagram of the underlying dynamical system to explain the existing single cell data in silencing...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mukhopadhyay, Swagatam, Nagaraj, Vijayalakshmi H., Sengupta, Anirvan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676882/
https://ncbi.nlm.nih.gov/pubmed/20655355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biosystems.2010.07.012
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