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Enforced expression of EBF in hematopoietic stem cells restricts lymphopoiesis to the B cell lineage
Mice deficient in early B cell factor (EBF) are blocked at the progenitor B cell stage prior to immunoglobulin gene rearrangement. The EBF-dependent block in B cell development occurs near the onset of B-lineage commitment, which raises the possibility that EBF may act instructively to specify the B...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC212730/ https://ncbi.nlm.nih.gov/pubmed/12970188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg464 |
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