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Enforced expression of EBF in hematopoietic stem cells restricts lymphopoiesis to the B cell lineage

Mice deficient in early B cell factor (EBF) are blocked at the progenitor B cell stage prior to immunoglobulin gene rearrangement. The EBF-dependent block in B cell development occurs near the onset of B-lineage commitment, which raises the possibility that EBF may act instructively to specify the B...

詳細記述

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書誌詳細
主要な著者: Zhang, Zheng, Cotta, Claudiu V., Stephan, Robert P., deGuzman, Cristina G., Klug, Christopher A.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC212730/
https://ncbi.nlm.nih.gov/pubmed/12970188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg464
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