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Conformation of full-length Bruton tyrosine kinase (Btk) from synchrotron X-ray solution scattering

Brutons’s tyrosine kinase (Btk) is a non-receptor protein tyrosine kinase (nrPTK) essential for the development of B lymphocytes in humans and mice. Like Src and Abl PTKs, Btk contains a conserved cassette formed by SH3, SH2 and protein kinase domains, but differs from them by the presence of an N-t...

Täydet tiedot

Tallennettuna:
Julkaisussa:EMBO J
Päätekijät: Márquez, José A., Smith, C.I.Edvard, Petoukhov, Maxim V., Lo Surdo, Paola, Mattsson, Pekka T., Knekt, Marika, Westlund, Anna, Scheffzek, Klaus, Saraste, Matti, Svergun, Dmitri I.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2003
Aiheet:
Articles
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC212716/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12970174/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg448
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