Conformation of full-length Bruton tyrosine kinase (Btk) from synchrotron X-ray solution scattering

Brutons’s tyrosine kinase (Btk) is a non-receptor protein tyrosine kinase (nrPTK) essential for the development of B lymphocytes in humans and mice. Like Src and Abl PTKs, Btk contains a conserved cassette formed by SH3, SH2 and protein kinase domains, but differs from them by the presence of an N-t...

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Detalhes bibliográficos
Main Authors: Márquez, José A., Smith, C.I.Edvard, Petoukhov, Maxim V., Lo Surdo, Paola, Mattsson, Pekka T., Knekt, Marika, Westlund, Anna, Scheffzek, Klaus, Saraste, Matti, Svergun, Dmitri I.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC212716/
https://ncbi.nlm.nih.gov/pubmed/12970174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg448
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