Chronic treatment with Carvedilol improves ventricular function and reduces myocyte apoptosis in an animal model of heart failure

BACKGROUND: β-blocker treatment has emerged as an effective treatment modality for heart failure. Interestingly, β-blockers can activate both pro-apoptotic and anti-apoptotic pathways. Nevertheless, the mechanism for improved cardiac function seen with β-blocker treatment remains largely unknown. Ca...

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Autors principals: Okafor, Chukwuka C, Perreault-Micale, Cynthia, Hajjar, Roger J, Lebeche, Djamel, Skiroman, Klara, Jabbour, George, Doye, Angelia A, Lee, Michael X, Laste, Nancy, Gwathmey, Judith K
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2003
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC212709/
https://ncbi.nlm.nih.gov/pubmed/12873352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6793-3-6
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