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Decreased Efficiency of Adenovirus-Mediated Gene Transfer in Aging Cardiomyocytes

BACKGROUND: Aging is an independent risk factor for the development of cardiovascular disease. Clinical application of myocardial gene transfer may be best suited in the elderly. In vivo gene transfer by adenovirus is less efficient in aging myocardium. METHODS AND RESULTS: When infected with adenov...

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Detalhes bibliográficos
Main Authors: Communal, Catherine, Huq, Fawzia, Lebeche, Djamel, Mestel, Celine, Gwathmey, Judith K, Hajjar, Roger J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1249504/
https://ncbi.nlm.nih.gov/pubmed/12615797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.CIR.0000051467.31874.29
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