Myofilament Calcium Regulation in Human Myocardium

BACKGROUND: We investigated whether decreased myofilament calcium contractile activation may, in part, contribute to heart failure. METHODS AND RESULTS: Calcium concentration required for 50% activation and Hill coefficient for fibers from nonfailing and failing human hearts at pH 7.1 were not diffe...

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Autors principals: Hajjar, Roger J., Schwinger, Robert H.G., Schmidt, Ulrich, Kim, Catherine S., Lebeche, Djamel, Doye, Angelia A., Gwathmey, Judith K.
Format: Artigo
Idioma:Inglês
Publicat: 2000
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1249501/
https://ncbi.nlm.nih.gov/pubmed/10758050
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