Isolation of mutants blocked in calicheamicin biosynthesis.

Blocked mutants of Micromonospora echinospora defective in the production of the potent antitumor agent calicheamicin are described. Analysis of intermediates produced by blocked mutants indicates a branched biosynthetic pathway. Mutants that produced some, but not all, calicheamicin forms are also...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	J Bacteriol
Päätekijät:	Rothstein, D M, Love, S F
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology (ASM) 1991
Aiheet:	Research Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC212544/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1938969/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.173.23.7716-7718.1991
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