Construction and characterization of a reovirus double temperature-sensitive mutant

The infectious reovirus RNA system was used to construct a mutant with two temperature-sensitive (ts) lesions in genome segments M2 and S2, respectively. The double mutant is about 300 times more ts than either of its parents, which are about 1,500 and 170 times more ts than their wild-type parent r...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Roner, Michael R., Nepliouev, Igor, Sherry, Barbara, Joklik, Wolfgang K.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1997
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21243/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9192650/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.13.6826
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