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Ribozymes that cleave reovirus genome segment S1 also protect cells from pathogenesis caused by reovirus infection

Reovirus genome segment S1 encodes protein σ1, which is the receptor binding protein, modulates tissue tropism, and specifies the nature of the antiviral immune response. It makes up less than 2% of reovirus particles and is synthesized in very small amounts in infected cells. Any antiviral strategy...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Shahi, Shweta, Shanmugasundaram, Ganapathy K., Banerjea, Akhil C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31186/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11274435/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.051013898
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