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Construction and characterization of a reovirus double temperature-sensitive mutant

The infectious reovirus RNA system was used to construct a mutant with two temperature-sensitive (ts) lesions in genome segments M2 and S2, respectively. The double mutant is about 300 times more ts than either of its parents, which are about 1,500 and 170 times more ts than their wild-type parent r...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Roner, Michael R., Nepliouev, Igor, Sherry, Barbara, Joklik, Wolfgang K.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21243/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9192650/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.13.6826
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