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Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: Tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines

Mycosis fungoides (MF) is a low-grade cutaneous T cell lymphoma of unknown etiology. In this report, the Jak/Stat (Janus kinase/signal transducer and activator of transcription) signaling pathway was investigated in tumor cell lines established from skin biopsy specimens from a patient with MF. Jaks...

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Main Authors: Nielsen, Mette, Kaltoft, Keld, Nordahl, Mette, Röpke, Carsten, Geisler, Carsten, Mustelin, Tomas, Dobson, Pauline, Svejgaard, Arne, Ødum, Niels
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences of the USA 1997
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC21232/
https://ncbi.nlm.nih.gov/pubmed/9192639
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