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Staphylococcal enterotoxins modulate interleukin 2 receptor expression and ligand-induced tyrosine phosphorylation of the Janus protein-tyrosine kinase 3 (Jak3) and signal transducers and activators of transcription (Stat proteins).

Staphylococcal enterotoxins (SE) stimulate T cells expressing the appropriate variable region beta chain of (V beta) T-cell receptors and have been implicated in the pathogenesis of several autoimmune diseases. Depending on costimulatory signals, SE induce either proliferation or anergy in T cells....

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Nielsen, M, Svejgaard, A, Röpke, C, Nordahl, M, Odum, N
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40557/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479924/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.24.10995
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