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Inhibition of protein phosphatase 2A induces serine/threonine phosphorylation, subcellular redistribution, and functional inhibition of STAT3

Signal transducers and activators of transcription (STATs) are rapidly phosphorylated on tyrosine residues in response to cytokine and growth factor stimulation of cell surface receptors. STATs hereafter are translocated to the nucleus where they act as transcription factors. Recent reports suggest...

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Detalhes bibliográficos
Main Authors: Woetmann, Anders, Nielsen, Mette, Christensen, Søren T., Brockdorff, Johannes, Kaltoft, Keld, Engel, Anne-Marie, Skov, Søren, Brender, Christine, Geisler, Carsten, Svejgaard, Arne, Rygaard, Jørgen, Leick, Vagn, Ødum, Niels
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17932/
https://ncbi.nlm.nih.gov/pubmed/10485875
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