Inhibition of protein phosphatase 2A induces serine/threonine phosphorylation, subcellular redistribution, and functional inhibition of STAT3

Signal transducers and activators of transcription (STATs) are rapidly phosphorylated on tyrosine residues in response to cytokine and growth factor stimulation of cell surface receptors. STATs hereafter are translocated to the nucleus where they act as transcription factors. Recent reports suggest...

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Dettagli Bibliografici
Autori principali: Woetmann, Anders, Nielsen, Mette, Christensen, Søren T., Brockdorff, Johannes, Kaltoft, Keld, Engel, Anne-Marie, Skov, Søren, Brender, Christine, Geisler, Carsten, Svejgaard, Arne, Rygaard, Jørgen, Leick, Vagn, Ødum, Niels
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC17932/
https://ncbi.nlm.nih.gov/pubmed/10485875
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