Inhibition of protein phosphatase 2A induces serine/threonine phosphorylation, subcellular redistribution, and functional inhibition of STAT3

Signal transducers and activators of transcription (STATs) are rapidly phosphorylated on tyrosine residues in response to cytokine and growth factor stimulation of cell surface receptors. STATs hereafter are translocated to the nucleus where they act as transcription factors. Recent reports suggest...

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Bibliographic Details
Main Authors: Woetmann, Anders, Nielsen, Mette, Christensen, Søren T., Brockdorff, Johannes, Kaltoft, Keld, Engel, Anne-Marie, Skov, Søren, Brender, Christine, Geisler, Carsten, Svejgaard, Arne, Rygaard, Jørgen, Leick, Vagn, Ødum, Niels
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1999
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC17932/
https://ncbi.nlm.nih.gov/pubmed/10485875
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