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Metabolic Flux Elucidation for Large-Scale Models Using (13)C Labeled Isotopes

A key consideration in metabolic engineering is the determination of fluxes of the metabolites within the cell. This determination provides an unambiguous description of metabolism before and/or after engineering interventions. Here, we present a computational framework that combines a constraint-ba...

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Detalhes bibliográficos
Main Authors: Suthers, Patrick F., Burgard, Anthony P., Dasika, Madhukar S., Nowroozi, Farnaz, Van Dien, Stephen, Keasling, Jay D., Maranas, Costas D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2121621/
https://ncbi.nlm.nih.gov/pubmed/17632026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2007.05.005
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