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Metabolic Flux Elucidation for Large-Scale Models Using (13)C Labeled Isotopes
A key consideration in metabolic engineering is the determination of fluxes of the metabolites within the cell. This determination provides an unambiguous description of metabolism before and/or after engineering interventions. Here, we present a computational framework that combines a constraint-ba...
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Autores principales: | , , , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
2007
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2121621/ https://ncbi.nlm.nih.gov/pubmed/17632026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2007.05.005 |
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