d-Amino acid oxidase and serine racemase in human brain: normal distribution and altered expression in schizophrenia

The N-methyl-d-aspartate receptor co-agonist d-serine is synthesized by serine racemase and degraded by d-amino acid oxidase. Both d-serine and its metabolizing enzymes are implicated in N-methyl-d-aspartate receptor hypofunction thought to occur in schizophrenia. We studied d-amino acid oxidase and...

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Bibliographic Details
Main Authors: Verrall, Louise, Walker, Mary, Rawlings, Nancy, Benzel, Isabel, Kew, James N. C., Harrison, Paul J., Burnet, Philip W. J.
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2007
Subjects:
Research Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2121142/
https://ncbi.nlm.nih.gov/pubmed/17880399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2007.05769.x
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