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Induction of insulin secretion in engineered liver cells by nitric oxide

BACKGROUND: Type 1 Diabetes Mellitus results from an autoimmune destruction of the pancreatic beta cells, which produce insulin. The lack of insulin leads to chronic hyperglycemia and secondary complications, such as cardiovascular disease. The currently approved clinical treatments for diabetes mel...

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Hlavní autoři: Muniappan, Latha, Özcan, Sabire
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2121102/
https://ncbi.nlm.nih.gov/pubmed/17941991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6793-7-11
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