Central nervous system nitric oxide synthase activity regulates insulin secretion and insulin action.

Systemic inhibition of nitric oxide synthase (NOS) with NG-monomethyl-L-arginine (L-NMMA) causes acute insulin resistance (IR), but the mechanism is unknown. We tested whether L-NMMA-induced IR occurs via NOS blockade in the central nervous system (CNS). Six groups of Sprague-Dawley rats were studie...

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Autores principales: Shankar, R, Zhu, J S, Ladd, B, Henry, D, Shen, H Q, Baron, A D
Formato: Artigo
Lenguaje:Inglês
Publicado: 1998
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC508988/
https://ncbi.nlm.nih.gov/pubmed/9769333
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