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Mechanisms involved in the effect of nitric oxide synthase inhibition on L-arginine-induced insulin secretion

1. A constitutive nitric oxide synthase (NOSc) pathway negatively controls L-arginine-stimulated insulin release by pancreatic β cells. We investigated the effect of glucose on this mechanism and whether it could be accounted for by nitric oxide production. 2. NOSc was inhibited by N(ω)-nitro-L-argi...

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Detalhes bibliográficos
Main Authors: Gross, R, Roye, M, Manteghetti, M, Broca, C, Hillaire-Buys, D, Masiello, P, Ribes, G
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564475/
https://ncbi.nlm.nih.gov/pubmed/9031755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700911
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