Peptidyl-transferase inhibitors have antiviral properties by altering programmed −1 ribosomal frameshifting efficiencies: Development of model systems

The effects of two peptidyl-transferase inhibitors, anisomycin and sparsomycin, on ribosomal frameshifting efficiencies and the propagation of yeast double-stranded RNA viruses were examined. At sublethal doses in yeast cells these drugs specifically alter the efficiency of −1, but not of +1, riboso...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Dinman, Jonathan D., Ruiz-Echevarria, Maria J., Czaplinski, Kevin, Peltz, Stuart W.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1997
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21205/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9192612/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.13.6606
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