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B cell tolerance in mice transgenic for anti-CD8 immunoglobulin mu chain

To analyze in vivo the induction of B cell tolerance against a T cell surface antigen, we generated transgenic mice expressing an anti-CD8.2 mu heavy chain gene. We show that self-specific B cells are efficiently tolerized if they express the membrane-bound form of the transgenic mu chain on their s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1991
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2119054/
https://ncbi.nlm.nih.gov/pubmed/1744576
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