Organ-dependent in vivo priming of naive CD4(+),but not CD8(+),T cells by plasmacytoid dendritic cells

Plasmacytoid dendritic cells (PDCs) play a pivotal role as cytokine-secreting accessory cells in the antimicrobial immune defense. In contrast, the capacity of PDCs to act as antigen-presenting cells in naive T cell priming remains unclear. By studying T cell responses in mice that lack conventional...

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Bibliographic Details
Main Authors: Sapoznikov, Anita, Fischer, Jens A.A., Zaft, Tami, Krauthgamer, Rita, Dzionek, Andrzej, Jung, Steffen
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2007
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118686/
https://ncbi.nlm.nih.gov/pubmed/17646404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062373
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