CNS Plasmacytoid Dendritic Cells Regulate the Severity of Relapsing Experimental Autoimmune Encephalomyelitis

Plasmacytoid dendritic cells (pDC) have both stimulatory and regulatory effects on T cells. pDCs are a major CNS-infiltrating DC population during experimental autoimmune encephalomyelitis (EAE), but unlike myeloid DCs (mDC) have a minor role in T cell activation and epitope spreading. We show that...

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Autors principals: Bailey-Bucktrout, Samantha L., Caulkins, Sarah C., Goings, Gwendolyn, Fischer, Jens A. A., Dzionek, Andrzej, Miller, Stephen D.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846244/
https://ncbi.nlm.nih.gov/pubmed/18453561
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