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Receptor editing: How B cells stay tolerant
In 1993, David Nemazee and Martin Weigert independently showed that autoreactive B cells could proofread, alter, and reexpress modified receptors to become nonautoreactive. This process, called “receptor editing,” has since gained prominence as the main mechanism of B cell tolerance.
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2007
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118665/ https://ncbi.nlm.nih.gov/pubmed/17823990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.2048fta |
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