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CD11b facilitates the development of peripheral tolerance by suppressing Th17 differentiation

Antigen-induced immune suppression, like T cell activation, requires antigen-presenting cells (APCs); however, the role of APCs in mediating these opposing effects is not well understood, especially in vivo. We report that genetic inactivation of CD11b, which is a CD18 subfamily of integrin receptor...

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Main Authors: Ehirchiou, Driss, Xiong, Ying, Xu, Guangwu, Chen, Wanjun, Shi, Yufang, Zhang, Li
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118631/
https://ncbi.nlm.nih.gov/pubmed/17562817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062292
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