CD11c depletion severely disrupts Th2 induction and development in vivo

Although dendritic cells (DCs) are adept initiators of CD4(+) T cell responses, their fundamental importance in this regard in Th2 settings remains to be demonstrated. We have used CD11c–diphtheria toxin (DTx) receptor mice to deplete CD11c(+) cells during the priming stage of the CD4(+) Th2 respons...

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Detalhes bibliográficos
Main Authors: Phythian-Adams, Alexander T., Cook, Peter C., Lundie, Rachel J., Jones, Lucy H., Smith, Katherine A., Barr, Tom A., Hochweller, Kristin, Anderton, Stephen M., Hämmerling, Günter J., Maizels, Rick M., MacDonald, Andrew S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947067/
https://ncbi.nlm.nih.gov/pubmed/20819926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100734
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