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Type I interferons produced by hematopoietic cells protect mice against lethal infection by mammalian reovirus
We defined the function of type I interferons (IFNs) in defense against reovirus strain type 1 Lang (T1L), which is a double-stranded RNA virus that infects Peyer's patches (PPs) after peroral inoculation of mice. T1L induced expression of mRNA for IFN-α, IFN-β, and Mx-1 in PPs and caused local...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118611/ https://ncbi.nlm.nih.gov/pubmed/17502662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061587 |
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