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Th2-driven, allergen-induced airway inflammation is reduced after treatment with anti–Tim-3 antibody in vivo
T cell immunoglobulin and mucin domain–containing molecule-3 (Tim-3) is a surface molecule that is preferentially expressed on activated Th1 cells in comparison to Th2 cells. Blockade of Tim-3 has been shown to enhance Th1-driven pathology in vivo, suggesting that blockade of Tim-3 may improve the d...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The Rockefeller University Press
2007
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118608/ https://ncbi.nlm.nih.gov/pubmed/17517968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062093 |
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