The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation

CD1d-restricted lymphocytes recognize a broad lipid range. However, how CD1d-restricted lymphocytes translate T cell receptor (TCR) recognition of lipids with similar group heads into distinct biological responses remains unclear. Using a soluble invariant NKT (iNKT) TCR and a newly engineered antib...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: McCarthy, Corinna, Shepherd, Dawn, Fleire, Sebastian, Stronge, Victoria S., Koch, Michael, Illarionov, Petr A., Bossi, Giovanna, Salio, Mariolina, Denkberg, Galit, Reddington, Faye, Tarlton, Andrea, Reddy, B. Gopal, Schmidt, Richard R., Reiter, Yoram, Griffiths, Gillian M., van der Merwe, P. Anton, Besra, Gurdyal S., Jones, E. Yvonne, Batista, Facundo D., Cerundolo, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118584/
https://ncbi.nlm.nih.gov/pubmed/17485514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062342
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados