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Intrarectal transmission, systemic infection, and CD4(+) T cell depletion in humanized mice infected with HIV-1

Intrarectal infection between men who have sex with men represents a predominant form of human immunodeficiency virus (HIV) transmission in developed countries. Currently there are no adequate small animal models that recapitulate intrarectal HIV transmission. Here we demonstrate that human lymphocy...

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Detalhes bibliográficos
Main Authors: Sun, Zhifeng, Denton, Paul W., Estes, Jacob D., Othieno, Florence A., Wei, Bangdong L., Wege, Anja K., Melkus, Michael W., Padgett-Thomas, Angela, Zupancic, Mary, Haase, Ashley T., Garcia, J. Victor
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118553/
https://ncbi.nlm.nih.gov/pubmed/17389241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062411
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