An ITAM-signaling pathway controls cross-presentation of particulate but not soluble antigens in dendritic cells

Dendritic cells (DC) possess a unique capacity for presenting exogenous antigen on major histocompatibility class I, a process that is referred to as cross-presentation, which serves a critical role in microbial and tumor immunity. During cross-presentation, antigens derived from pathogen-infected o...

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Hlavní autoři: Graham, Daniel B., Stephenson, Linda M., Lam, Siu Kit, Brim, Karry, Lee, Hyang Mi, Bautista, Jhoanne, Gilfillan, Susan, Akilesh, Shreeram, Fujikawa, Keiko, Swat, Wojciech
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118522/
https://ncbi.nlm.nih.gov/pubmed/17984307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071283
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