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Myosin IIA is required for cytolytic granule exocytosis in human NK cells

Natural killer (NK) cell cytotoxicity involves the formation of an activating immunological synapse (IS) between the effector and target cell through which granzymes and perforin contained in lytic granules are delivered to the target cell via exocytosis. Inhibition of nonmuscle myosin II in human N...

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Bibliografske podrobnosti
Main Authors: Andzelm, Milena M., Chen, Xi, Krzewski, Konrad, Orange, Jordan S., Strominger, Jack L.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118468/
https://ncbi.nlm.nih.gov/pubmed/17875677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071143
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