Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1

Glucocorticoids (GCs), which are used in the treatment of immune-mediated inflammatory diseases, inhibit the expression of many inflammatory mediators. They can also induce the expression of dual specificity phosphatase 1 (DUSP1; otherwise known as mitogen-activated protein kinase [MAPK] phosphatase...

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Bibliographic Details
Main Authors: Abraham, Sonya M., Lawrence, Toby, Kleiman, Anna, Warden, Paul, Medghalchi, Mino, Tuckermann, Jan, Saklatvala, Jeremy, Clark, Andrew R.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2006
Subjects:
Brief Definitive Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118371/
https://ncbi.nlm.nih.gov/pubmed/16880258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060336
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