Regulation of the energy sensor AMP-activated protein kinase by antigen receptor and Ca(2+) in T lymphocytes

The adenosine monophosphate (AMP)–activated protein kinase (AMPK) has a crucial role in maintaining cellular energy homeostasis. This study shows that human and mouse T lymphocytes express AMPKα1 and that this is rapidly activated in response to triggering of the T cell antigen receptor (TCR). TCR s...

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Detalhes bibliográficos
Main Authors: Tamás, Peter, Hawley, Simon A., Clarke, Rosemary G., Mustard, Kirsty J., Green, Kevin, Hardie, D. Grahame, Cantrell, Doreen A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Brief Definitive Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118355/
https://ncbi.nlm.nih.gov/pubmed/16818670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20052469
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