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The clone size of peripheral CD8 T cells is regulated by TCR promiscuity

Positive selection in the thymus and peripheral T cell survival depend on T cell receptor (TCR)–major histocompatibility complex (MHC) interactions, but it is not yet clear if both events follow exactly the same rules. We studied peripheral T cell survival and clone sizes in conditions of progressiv...

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Detalhes bibliográficos
Main Authors: Hao, Yi, Legrand, Nicolas, Freitas, Antonio A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118336/
https://ncbi.nlm.nih.gov/pubmed/16769997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20052174
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