The BRAF–MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells

The mitogen-activated protein kinase (MAPK) pathway is frequently activated in human cancers, leading to malignant phenotypes such as autonomous cellular proliferation. Here, we demonstrate a novel role of the activated MAPK pathway in immune evasion by melanoma cells with the mutation of BRAF, whic...

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Bibliographic Details
Main Authors: Sumimoto, Hidetoshi, Imabayashi, Fumie, Iwata, Tomoko, Kawakami, Yutaka
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2006
Subjects:
Brief Definitive Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118331/
https://ncbi.nlm.nih.gov/pubmed/16801397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051848
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