IFNγ-dependent, spontaneous development of colorectal carcinomas in SOCS1-deficient mice

Approximately 20% of human cancers are estimated to develop from chronic inflammation. Recently, the NF-κB pathway was shown to play an essential role in promoting inflammation-associated cancer, but the role of the JAK/STAT pathway, another important signaling pathway of proinflammatory cytokines,...

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Detalhes bibliográficos
Main Authors: Hanada, Toshikatsu, Kobayashi, Takashi, Chinen, Takatoshi, Saeki, Kazuko, Takaki, Hiromi, Koga, Keiko, Minoda, Yasumasa, Sanada, Takahito, Yoshioka, Tomoko, Mimata, Hiromitsu, Kato, Seiya, Yoshimura, Akihiko
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Brief Definitive Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118311/
https://ncbi.nlm.nih.gov/pubmed/16717119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060436
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