Loss of SOCS3 in T helper cells resulted in reduced immune responses and hyperproduction of interleukin 10 and transforming growth factor–β1

Suppressor of cytokine signaling (SOCS)3 is a major negative feedback regulator of signal transducer and activator of transcription (STAT)3-activating cytokines. Transgenic mouse studies indicate that high levels of SOCS3 in T cells result in type 2 T helper cell (Th2) skewing and lead to hypersensi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kinjyo, Ichiko, Inoue, Hiromasa, Hamano, Shinjiro, Fukuyama, Satoru, Yoshimura, Takeru, Koga, Keiko, Takaki, Hiromi, Himeno, Kunisuke, Takaesu, Giichi, Kobayashi, Takashi, Yoshimura, Akihiko
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118269/
https://ncbi.nlm.nih.gov/pubmed/16606674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20052333
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados