Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors

Introduction of heterologous anti–glomerular basement membrane antiserum (nephrotoxic serum, NTS) into presensitized mice triggers the production of IgG anti-NTS antibodies that are predominantly IgG2b and the glomerular deposition of pathogenic immune complexes, leading to accelerated renal disease...

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Bibliographic Details
Main Authors: Kaneko, Yoshikatsu, Nimmerjahn, Falk, Madaio, Michael P., Ravetch, Jeffrey V.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2006
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118246/
https://ncbi.nlm.nih.gov/pubmed/16520389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051900
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