ATM regulates ATR chromatin loading in response to DNA double-strand breaks

DNA double-strand breaks (DSBs) are among the most deleterious lesions that can challenge genomic integrity. Concomitant to the repair of the breaks, a rapid signaling cascade must be coordinated at the lesion site that leads to the activation of cell cycle checkpoints and/or apoptosis. In this cont...

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Bibliografiske detaljer
Main Authors: Cuadrado, Myriam, Martinez-Pastor, Barbara, Murga, Matilde, Toledo, Luis I., Gutierrez-Martinez, Paula, Lopez, Eva, Fernandez-Capetillo, Oscar
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2006
Fag:
Brief Definitive Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118201/
https://ncbi.nlm.nih.gov/pubmed/16461339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051923
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