Triggering CD40 on endothelial cells contributes to tumor growth

Inflammatory cells can either promote or inhibit tumor growth. Here we studied whether CD40, a key molecule for adaptive immune response, has any role in mammary carcinogenesis of BALB/NeuT transgenic tumor-prone mice. We transferred the HER2/neu oncogene into CD40-null background to obtain the CD40...

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Bibliografiske detaljer
Main Authors: Chiodoni, Claudia, Iezzi, Manuela, Guiducci, Cristiana, Sangaletti, Sabina, Alessandrini, Isabella, Ratti, Chiara, Tiboni, Francesca, Musiani, Piero, Granger, D. Neil, Colombo, Mario P.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2006
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118135/
https://ncbi.nlm.nih.gov/pubmed/17043144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060844
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