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Leukocyte, Rather than Tumor-produced SPARC, Determines Stroma and Collagen Type IV Deposition in Mammary Carcinoma

Secreted protein, acidic and rich in cysteine (SPARC), also known as osteonectin or BM-40, is a Ca(2+)-binding matricellular glycoprotein involved in development, wound healing, and neoplasia. However, the role of SPARC in tumors is ill defined mostly because it is expressed by both tumor and stroma...

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Detalhes bibliográficos
Main Authors: Sangaletti, Sabina, Stoppacciaro, Antonella, Guiducci, Cristiana, Torrisi, Maria Rosaria, Colombo, Mario P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194114/
https://ncbi.nlm.nih.gov/pubmed/14610043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030202
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