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Immune Checkpoint Ligand Reverse Signaling: Looking Back to Go Forward in Cancer Therapy

The so-called immune checkpoints are pathways that regulate the timing and intensity of the immune response to avoid an excessive reaction and to protect the host from autoimmunity. Immune checkpoint inhibitors (ICIs) are designed to target the negative regulatory pathways of T cells, and they have...

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Bibliografiset tiedot
Julkaisussa:Cancers (Basel)
Päätekijät: Lecis, Daniele, Sangaletti, Sabina, Colombo, Mario P., Chiodoni, Claudia
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563035/
https://ncbi.nlm.nih.gov/pubmed/31060225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11050624
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