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Immune Checkpoint Ligand Reverse Signaling: Looking Back to Go Forward in Cancer Therapy
The so-called immune checkpoints are pathways that regulate the timing and intensity of the immune response to avoid an excessive reaction and to protect the host from autoimmunity. Immune checkpoint inhibitors (ICIs) are designed to target the negative regulatory pathways of T cells, and they have...
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| Published in: | Cancers (Basel) |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
MDPI
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6563035/ https://ncbi.nlm.nih.gov/pubmed/31060225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11050624 |
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